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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCSH
All Species:
30.3
Human Site:
Y502
Identified Species:
55.56
UniProt:
P14314
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14314
NP_001001329.1
528
59425
Y502
T
E
P
S
R
C
E
Y
L
M
E
L
M
T
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542057
593
66107
Y567
T
E
P
S
R
C
E
Y
L
M
E
L
M
T
P
Cat
Felis silvestris
Mouse
Mus musculus
O08795
521
58774
Y495
T
E
P
S
R
C
E
Y
L
M
E
L
M
T
P
Rat
Rattus norvegicus
NP_001100276
525
59200
Y499
T
E
P
S
R
C
E
Y
L
M
E
L
M
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510649
692
76488
X543
T
D
P
T
L
X
X
X
X
P
P
P
R
S
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086185
514
57354
R487
T
S
T
S
E
P
S
R
C
E
Y
L
M
E
F
Zebra Danio
Brachydanio rerio
NP_957347
529
59566
Y503
S
E
P
S
R
C
E
Y
L
M
E
F
I
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609844
548
61521
Y522
S
E
P
N
R
C
E
Y
Y
F
E
F
E
T
P
Honey Bee
Apis mellifera
XP_625125
493
56012
R467
V
S
V
T
E
P
S
R
C
E
Y
A
M
E
F
Nematode Worm
Caenorhab. elegans
NP_496073
507
58044
K482
V
E
V
T
E
P
A
K
C
E
Y
L
F
T
F
Sea Urchin
Strong. purpuratus
XP_789169
523
60041
Y496
S
E
P
D
R
C
V
Y
Q
F
E
F
T
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146004
602
67827
Y567
D
E
P
S
R
C
E
Y
V
A
V
L
S
T
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04924
702
79889
Y677
H
E
A
T
K
C
N
Y
I
F
D
V
V
G
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
80.9
N.A.
86.7
85.2
N.A.
53.6
N.A.
62.3
62.3
N.A.
38.3
41.4
36.7
43.7
Protein Similarity:
100
N.A.
N.A.
83.9
N.A.
92.9
91.6
N.A.
61.9
N.A.
77
76.7
N.A.
53.2
57.9
56.4
59.4
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
N.A.
26.6
80
N.A.
60
6.6
20
53.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
33.3
N.A.
26.6
93.3
N.A.
73.3
13.3
26.6
60
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
48.6
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
66.6
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
70
0
0
24
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
77
0
0
24
0
54
0
0
24
54
0
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
24
0
24
8
0
24
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
39
0
0
54
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
39
0
0
47
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
70
0
0
24
0
0
0
8
8
8
0
0
70
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
62
0
0
16
0
0
0
0
8
0
0
% R
% Ser:
24
16
0
54
0
0
16
0
0
0
0
0
8
8
0
% S
% Thr:
47
0
8
31
0
0
0
0
0
0
0
0
8
70
0
% T
% Val:
16
0
16
0
0
0
8
0
8
0
8
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
8
0
24
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _